How many transistors used depends on the (1)power handling, (2)distortion and (3)beta droop at high current.
(1)Power handling is very obvious, you need more transistors to handle more power. Don't just look at the 200W rating of a lot of transistors, you have to look at the SOA ( safe operating area) curve of the transistor. At higher temperature, the 200W transistor cannot handle even close to that.
(2)The following ONLY applies to the most common emitter follower output stage(EF) in class AB power amp. Main problem of class AB is the crossover distortion. Crossover distortion of output stage depends on the load it's driving. Ball park is distortion double when the load it is driving is halfed. That is distortion almost doubled from the spec of driving 8ohm load if you use it to drive 4ohm load. Or look at it in another way, the distortion halved from driving 8ohm if the load doubled to 16ohm. This is very important to know and use it as guideline.
Suppose your amp has only one pair of EF as output stage ( complementary output pair is NPN and PNP). So the one output pair is driving 8ohm load and produce a certain amount of distortion. Now if you double the output pair to two pairs. So two pairs are driving the same 8ohm load. BUT NOW, each pair is driving half of the load.......That is as if each pair is driving a 16ohm load ( half the amount of load of 8ohm). So, the distortion is almost half.
Now the same theory applies further, If you amp has 4 pairs of EF stages, each pair drive 1/4 of the load or 32ohm. Distortion lower another half from two pairs or 1/4 of a single pair. Same theory applies to 8 pairs...........and so on. Of cause there are law of diminish return. Anything over 32ohm load is so low it's not significant anymore. But why people use 8 pairs? this is because impedance of the speakers are not constant with frequency. Some dip as low as 2ohm or under. If you look at the more exotic speakers, they are mostly lower than 8ohms, more like 4ohm. It is reasonable they dip even below 2ohm. That's when you need more pairs. That's the reason I design with 9 pairs of EF pairs in my current design. My first design was 5 pairs, result was good, I just want to improve more. Power section distortion is the major component of the distortion of class AB power amps.
3) All transistors have beta droop at high current, just look at the graph in data sheets. The best transistor pair are MJW1302/3281 by On Semi, it still starting to droop above 6 or 7A. So if you have an amp with 50V supply rail, and if you can swing to 45V. If you drive a 4ohm speaker, peak current is 45/4=11.25A. You definitely need at least 2 pairs of output transistors for output stage. Beta droop put extra load on the driver transistors which reflect back to the VAS stage ( voltage amplifier stage) of the power amp. That's the reason good amp design use 3EF instead of 2EF stage. 3EF meaning emitter follower pre-driver driving the driver stage, then the driver stage drives the big output transistors. With all the betas, the effect to the VAS stage is minimized even though the beta droop happens at the big transistors.
Hope this help. This is why my amp has 9 pairs of output transistors and 3EF, all to lower distortion. And I am designing for 120W into 4ohm only. It's not the amount of watts, it's the quality of the watts. I get 8W of class A into 4ohm and 16W into 8 ohm. It's going to be a class A at my listening level.
Now, the most important (2) does not apply to class A amplifiers. By definition of class A, both NPN and PNP transistor pairs are ALWAYS ON, NEVER TURNS OFF, unlike the class AB where one is off while the other one is driving in one direction. There is no crossover distortion, you don't need to worry about (2), as you will notice, class A amp usually have less pairs of transistors. (1) and (3) still applies. There is no way out of (1) and (3) but more pairs. BUT when you see class A, you better ask what load. Amp that guaranty class A for 8ohm speaker might not be class A driving 4ohm speaker. Result might be worst than a well designed class AB when a class A amp goes out of class A into class B.