Not likely. The Shure M80E was sold preinstalled in a Garrard headshell (unlike the earlier Shure M99 for the Garrard Type A which came in a Shure-built headshell). There is no room under the M80's mounting bracket for the Lab 80's auxiliary weight.
The M80E could track to a maximum of 1.5 grams; higher, and the cartridge would retract on its spring suspension. It was sold for the Garrard Lab 80 and Type A70; and a version was also built into Dual headshells, M80-D for the Dual 1009 and M80-D19 for the Dual 1019 and 1009SK.
The cartridge wires on the M80E were a single strand of copper inside a woven fabric "shield" built for maximum flexibility for the cartridge to "float" freely on its spring suspension. Unfortunately the single strand of copper could often break over time. You could remove the broken wire and solder in a new, conventional cartridge wire but anyone who has tried knows that it is very difficult to solder a Lab 80 headshell connector because a bit of excess heat will melt the plastic.
For that matter, you could remove the M80 and its suspension...it mounted via standard cartridge mounting screws
. Carefully unplug the four wires and substitute another cartridge, with standard 1/2 inch mounting.
The M80 cartridge body was the same as the Shure M44/M55, modified to mount on the M80's spring suspension. The stylus for the M80E was the N55E.
The Shure instruction sheet (link below) for the M80E offered to repair a damaged stylus, if the diamond tip was still there and intact...for $6.00; the equivalent of about $44 today.
Shure M80E instructions