The QA403 negates the need for a soundcard. It is self-contained with a DAC and a tone generator, and you use the supplied application for your measurements and analysis.
You'll need BNC cables, RCA adapters, 50 or 75 Ohm BNC terminations.
Also, download the manual, and read the WIKI page - each are linked on the QA web site.
In testing mode, the QA403 produces bursts from the generator when in test mode, which is why the QA451 is not a problem to use for testing, but if you select the idle feature, it outputs continuous tones, so you do want to read the manuals carefully.
If you have this unit, you will probably get better results and much more easily than the REW/soundcard/generator approach - that has been my experience, at least.
I have an HP339A, HP8903B, Amber, and Sound Technology distortion analyzers, as well as the QA403, a soundcard, and the Cosmos system. Of all, the standalone HP are easiest to use and accurate, but performance is not as high as the QA403 or Cosmos. I use them for older audio gear, and for fast measurements to confirm proper operation, rather than fully characterize (to my abilities) the DUT. The Cosmos is quieter than the QA403, but a true pain in the butt to use, as the documentation is nonexistent.
Figure out what you want to measure and the end goal of the measurements, and pick the right gear. You are probably there already. Keep them both and also make a good, noninductive dummy load for when you need it.