The lower the speaker impedance, the more power your amp is forced to deliver. IOW, the lower the impedance, the more your amp is stressed.
Eight ohms is a safe load for virtually any amp.
Four ohms can be pushing it unless you have a VERY rugged amp.
Two ohms is generally only for automotive use where that impedance is fairly common and many amps are designed with that in mind.
As was said, know what your amp can handle.