Well, I can't say that I have done a side-by-side test, but I have a system upstairs with a pair of Epicure M50s, with Dayton 1% caps in them, original masonite tweeters, and refoamed mid-woofers. Kenwood KA-3500 amp, Pioneer DV563 for movies and cds.
Downstairs was a Cambridge Audio A500/D500SE/T500/Music Hall mmf-5 into a pair of Human Speakers 61+.
The M50s are like old friends. They have been mine, since new, more than 40 years ago. The sound is comfortable, and, when called upon, for movies, can exhibit a surprising amount of dynamics. They are in my wife's primary system. Other than movies, the most exercise they get is Barry Manilow or Meat Loaf.
Downstairs, the Humans are used primarily for background music, when entertaining, or while shooting pool. I do confess that I have had to stop, mid-shot, to listen to a particular passage, and, occasionally, will just sit and listen.
Neither of those are my primary system, but both are very satisfying. I think the Humans' sound is, for lack of a better term, more 'modern', detailed in upper ranges. I do enjoy listening to jazz records on that system.
I did put Dayton 1% caps in the Humans, also, just because.
I don't think you'll find one weaker than the other, just different. Basically, each is representative of its time. If you like the 'vintage New England' sound, stick with the masonite. If you like a little more 'sparkle', go with the Human aluminum tweeter. both are inverted domes, and more alike than different.
An email conversation I had with Winslow Burhoe contained his assessment of Huy Powell's update of his, Winslow's, tweeter. He said that Huy is building the tweeter that he was working on, as the successor to his original inverted dome. At that point, I had no more reservations about buying a pair of Human speakers.
If you don't like the metal tweeters, you can always sell them, and source a replacement pair of masonite tweeters.
