No, the 500C is fixed bias, as are almost all 7591 / 7868 amplifiers (EICO ST40 is only exception I know of). Fixed bias uses a negative grid voltage to bias tubes, cathode bias has a cathode resistor to develop a positive cathode voltage (so grid is negative with respect to cathode). (Confusing, how we call adjustable bias "fixed" bias).
Grid leakage can occur from multiple causes, and amount is impossible to predict (though lower is better!) First is gas, leakage from seals or outgassing from overheated plates or mica - positive ions will be attracted to the grid. Second is conductive deposits on mica insulators, again probably from overheating. And there's grid emission - if it gives off electrons, it goes positive. Overheating the grid or deposition of cathode material on the grid (again likely from overheating) can cause this. So... if materials in modern tubes are not as good as the old ones, grid emission is likelier, especially if tubes are run near max ratings. Once it gets high enough to affect bias, it's the beginning of the end - tube gets hotter, grid emission increase, bias drops further, gets even hotter, etc. So back off the idle current a bit and hope your output tubes die of old age, not catastrophically.