Fuses are overrated.
The only thing I ever heard about fuses making a difference in the sound was from Heathkit I believe, though other manufacturers (are they really ? lol) might have agreed, is odd order distortion caused by the fuse element heating up on bass notes and increasing in resistance.
Heath decided to fix this by putting the fuses inside the feedback loop. The efficacy of that is debatable.
You need figures out the ass to know how much this matters. First of all the thermal mass of the fuse element. And then its temperature to resistance coefficient. Then you get to figure out if the fuse is causing 0.001 or 0.0015% distortion, and at what power level.
And then you get to compare that to the distortion in the woofer, and how much IM might be caused by this effect. I think unless you got some really high end speakers like Quad ESLs or something, you are going to have a damn hard time hearing any difference, especially on most material.
The whole premise of a fuse introducing distortion is based on its heating and cooling during the audio cycle at low frequency. At high frequency, even the small fuses have too much thermal mass to have any real effect. At low frequency, because of the thermal mass, it is going to cause phase shift as well as odd order distortion, and that might actually be more hearable than the distortion. All depends on what you're listening to. And your ears and speakers of course.
Tellyawhat, the odds against any amp shorting out and blowing your woofers at any given moment are so astronomical, jump them. I don't mean permanently, but if you want a side by side comparison take a toggle switch and wire it across the fuses. See if you can hear a difference with the switch on or off. Keep the wires short. this should satisfy your curiosity better than buying fuses, changing them and then turning the thing back on and all that.
Another thing you could do is take the original fuses and a calibrated power supply and see just how much the resistance changes with DC current. This will give you a maximum factor. However, you'll probably blow the fuse about the time you get any useful reading.
And that will tell you this much - by the time that fuse makes any distortion, your woofer is going to be making alot more unless you got four figures into speakers. But don't let me discourage you from experimenting, I am just telling it like it is. If you prove me wrong then I shall have learned something.