When you take the room completely out of the equation, the nearfield listening experience of cans can sound amazingly clear, but for most of the reasons above I rarely listen to music on my headphones, including my Sennheiser HD600's which are my favorites of what I own.. But one of the biggest reasons is that headphones in general give me ear fatigue, and aggravate my right ear tinnitus. Always have, and I can remember this from 40 years ago. This isn't the case with my speakers. It is hard to say why this is. I read somewhere that sound going directly into the ear can be more damaging. I don't know if this is true or if I am simply unconsciously playing them at a higher db (at the ear drum) because I am trying to compensate for a lack of something, probably bass that is felt in the body when listening on speakers capable of good clean bass. Anyway, while there can be uses for cans, I would far rather listen to good speakers in a good room.