I have, with identical amps top/bottom (4), with different amps top/bottom solid-state, with solid-state tri-amped, solid-state bottom and tube top. I have used passive with full-range into all amps driving into passive crossovers, network before amps using analog active crossover (both 3-way and 2-way), and using DSP for crossover and shaping both 2-way and 3-way.
I think that there are advantages to be had by a properly set up multi-amplifier bi/tri-amp setup, I am not a believer in tubes as I can’t see value in adding distortion when a proper modern SS unit will be cleaner, so “warmth” added isn’t something I look for, that was fun but I never felt it sounded as good as SS top and bottom.
Most recently I moved toward 2-way, which simplified the tri-amp into bi-amp, and in my mind made more sense, but comparing what I was able to accomplish sans passive crossover to what my speaker manufacturer was able to accomplish in the crossover (in high-end speakers anyway) I was not able to near nor measure any significant difference, so I further simplified and went back to using 2-way speakers with the internal crossover that a multi-million-dollar R&D budget created, ... and find it to be something I could not improve upon.
Yes, the journey was fun, a lot was learned, and I feel that if you have the time, money, and curiosity to do so it is well worth experimenting with crossovers and multi-amp setups. There is just so much that can be tailored to your individual taste, and it looks soooo cool! The downside is that it isn’t simple, doing it properly takes a good quality crossover (DSP) and good quality calibrated mic with software to measure and do the exact thing that the original crossover was doing (band-pass, high-pass, low-pass, those are easy but many higher-quality speaker crossovers also do a fair amount of shaping). Then, every time something changes (different speakers, different amp, etc.) you are starting over, which is what made me lose interest since I tend to upgrade / change things occasionally and was tired of the long process of tuning everything every time. Also, if you like to do A/B comparisons or swap gear occasionally it is complicated (although my big DSP saves many many configurations, just need to name them appropriately for recall later).
In short: Do it, it is worth the time and you will learn a lot about your personal preferences.