I havent had any issues yet.
I have all of my audio grounds soldered to a Romex bus wire.
Same on the power supply side.
The chassis will be the higher impedance ground vs the fat copper wire soldered between the capacitors negative terminal and my "house earth"
Any stray electrical signals which touch the chassis must have not only a low impedance path to earth ground, there must be no path for signal (including power supply ripple current) to back feed onto our audio signal ground. Same for case ground it should pass those signals directly o the house earth terminal and never on a conductor that has signal or power grounds.
Electrolysis between parts, I havent seen yet, that's more of a problem in dirty environments.
I remember working on a Porsche transmission made of magnesium, the bolts all had a little plastic seal to keep crud out, crud leads to electrolysis, and eventually your bolts corrode into your case and the whole thing is scrapped.
I'm not building magnesium sand rails, so horses for courses.
Btw, the "cage" on that "rail" was made of black iron plumbing pipe.
Not chromoly, not DOM, plumbing pipe, threads still attached.
Waste of a perfectly good Porsche motor if you ask me...
Back on topic...
You shouldn't rely on screws and contact for ground, unless you have to.
For an aluminum chassis, you can't exactly solder to, use a star washer ground lug, and screw it into clean threads, and dont pass signal current through it.
Back to drive lines for a minute.
In learning how they work one of our tasks was to list power flow.
Starting at the torque converter and ending at the tail shaft, we were expected to list every part in order that the power moved through in each gear. At one point I could do it too.
Same goes for currents in your amplifier.
You know your design much better when you have a running list in your head of the components that each individual circuit passes through and the order, and direction in which it does so..
All for a better understanding of everything.