You say both amplifiers produce a hissing noise regardless of the speakers connected to the amps. It would be unusual for two amps to fail in the exact same way with the same symptoms. That indicates that the source of noise is likely external to the amps. I assume that you hear the hiss equally from both speakers/channels.
Try the following:
Unplug everything except power and the speakers from your amp. Turn the gain pots all the down. Do you still hear the noise?
Do you plug your amps into a surge suppressor or UPS? If so, remove it and test again.
Do you have any other electrical equipment next to your amp? Like a WiFi router, computer, laptop, Apple TV or Express, or something? Turn all that stuff off or move it into another room. You want to eliminate all sources of electromagnetic interference (EMI) near your amp, speakers, and speaker cables. Still have the noise?
If you still have noise, you can plug the amp into another circuit in your house, that is, another place in the house that has a different circuit breaker controlling the outlet. Plug the cord directly into the wall socket. Make no other connection to your amp. I suggest that you physically move the amp and a speaker to the new location. Do you still hear the noise?
If you have eliminated all external noise sources and the noise is still heard from both amps, then I can only conclude that your amps both suffer from the same ailment. Freddymac2 says it is likely generated in your front end. That is the portion of the amplifier before the signal is amplified. You say the noise does not change when changing the gain pots, then the noise must originate after the gain stage.
All this tells us is where we need to start checking voltages and waveforms with a scope. If the noise is that objectionable, you may want to take one amp in for service.