Well, lets think about this for a minute. Most speakers have cross-over networks. Cross-over networks are not brick walls. So, if a tweeter crosses over at say 5,000 cycles, and we happen to boost the EQ up about 8 db at that particular frequency or slightly lower frequency, and the speaker has the typical 12db per octave slope (every octave, its 12 db less), the added signal strength may add more signal strength to the cross-over at lower frequencies, where added power may harm the tweeter (perhaps even approaching its resonance frequency, or even lower). The same can be said for the mid-range.
When we adjust equalizers to more then a few db, we upset the natural, overall flatness of the recording (at least on paper). The "out of balance" signal is (depending on level), going to put added stress on the drivers, due to the cross-over slope.
I also agree with twiii's comment, tho we are coming at from slightly different angles.
Think of how many JBL-L100s were damaged by EQs. The user had no idea that the mid and tweeter were simple, 6db per octave slopes. Also, the woofer had no coil or cap, just rolled off.
Not bashing JBLs, (I owned a pair myself).
That is why tone controls are at the extremes, like 50hz and 10,000 hz.