These were running with the Russian and Chinese KT66 tubes made in the '00s. I would get 500 hours per quad before they got dull, glass turned brown, or they just biased poorly. But they were being used as a main amp in that time, so I'd probably do 1000+ hours/year. Being Class A amps, they are very hard on the output tubes as they run them at max plate dissipation. Most new KT66s are running with slightly red plates at these levels, but I've never had a failure or runaway. That said, I use them only on special occasions lately, so I've had one set of output tubes for the past 10+ years at this point.
And that is exactly why I don’t buy vintage tubes with brown or white on the getter flash. One time someone tried to trade me a bunch of brown getter flash tubes for an amp and none of them held bias. Of course the seller claimed they were good.