For a 'new' project, you see a default power supply schematic. Right click on the left side of the schematic to 'yellow' select the power transformer and diodes region. Right click that yellowed region to 'change' and select vacuum tube and full wave. Double click on the transformer symbol and you get "edit transformer properties' dialog box. Click the small "..." box beside Ohms to bring up a Source impedance calculator box. Insert the primary winding voltage and resistance. Insert the secondary details (this is for one 'half' of the secondary winding (ie. 422V and 84 ohm - assuming 84 ohm is the resistance from one anode to CT), and 'ok' back to the main schematic.
You should then get 422V and 801 ohm showing in the main schematic. Double click the valve and change to 5AR4. For starters, just double click on the capacitor and change to 50uF. Go to Options menu and click on 60Hz in Mains Frequency, and ensure soft start is not ticked. Save the .psu file to your project directory.
Choose 300ms and 0 secs delay in the simulate area. Click the Simulate button, then tick the V(C1) and I(R1) result parameters, and the output waveforms should show output voltage and current rising to 400VDC and 80ma.