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Is there an "additive" for cleaning fuel injectors?

Unless your engine is knocking under load or acceleration, higher octane fuel is a waste of money. A statistician that used to work for Exxon or one of the big oil companies told me that a long time ago. Your local parts store will have many different kinds of injector cleaners.

If your engine is designed or tuned for higher octane fuel (like my mildly upgraded 6.0 LS) then you definitely want to run the gas it's designed/tuned for. My engine won't blow up if I dump 87 octane in it, but it certainly lets you know its not happy.
 
Higher octane requirements usually are for a reason. These days cars can pretty much deal with lower octane fuel (octane being anti-knock and not a measure of energy or BTUs BTW) using knock sensors and reducing boost / retarding spark/ignition, but there’s a cost.

That cost is often very minor, … the fuel mileage and emissions numbers that are published are based on the fuel that is recommended/required, and either (or both) could be worse with lower octane fuel. It probably has no negative effect on a modern engine’s longevity.

In my gasoline turbo cars I have been able to document (40k miles/year) about a 20% highway mileage gain by using the (recommended) higher-octane fuel, … which pretty much covers the difference in price, so in a way the extra fuel range and extra power is free. The engine is able to run a more advanced ignition and slightly higher boost, both adding efficiency and burning cleaner. For me the big gain is stopping 20% less often for fuel. Premium fuel also usually has a better additive package which could mean a cleaner and better running engine.

Diesels are a different beast, I live where cold weather brings winterized diesel, … essentially cut more with kerosene to lower its wax-point with a corresponding reduction in cetane and therefore lower power and mileage, I can lose close to 20% in fuel mileage on winter diesel.
 
Top tier gas for my vehicles. One of my boys always bought the cheapest for his 2012 Beetle. It started to run a bit rough so he decided to use top tier gas and it ran better after a few tanks. Told him to try some Seafoam injector cleaner and now says it's back to it's old self. I stick with Shell or other top tier stations. Found out recently that Valero is a top tier station. Cars cost too much to try and save a few pennies using low quality gas that will cost you in the long run.

I've never noticed a difference in the mileage between regular and premium and certainly not enough to justify the cost. 20% is a huge jump and would be noticeable without calculating it at the pump. The average cost of premium is 20-30% more so you don't save any money. Used alcohol free gas in my Maverick and got a minor improvement in milage but nowhere near enough to justify the cost. The only turbo 4 that absolutely needed premium was a 2002 VW Passat. It would throw a lean condition code. Since then all the turbos recommend premium but run fine on regular if it's just everyday driving(this is from the manual) and premium if towing which means to also use premium if your going to track your car or other stressful driving. If your car is designed to use regular to premium you'll see no difference in mileage according to what I've found from research and real world driving.

Direct injection is a problem with modern engines, So much so they now have blended port and direct injection to stop the problem with the back of the valves gunking up. That gunk can cause rough running, low power. Glad my 2025 Maverick uses port.
 
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