First, swap the cables to the speakers, left for right. This will test to see if the missing high-end in one speaker travels with it or stays on that side. If it travels, the problem is in the speaker. If it remains in the same channel, but now the problem is with the other speaker, then the problem is your source.
Assuming the problem is in the speaker, remove it and the tweeter from the 'good' unit and swap them. If the 'dead' speaker wakes up, you may have a dead tweeter. If the dead speaker is still dead on the high-end, then possibly you have a problem with your crossover network.
At this point, you most likely have some idea where to look. It is not uncommon for tweeters to die, and it's not uncommon for capacitors in crossovers to die, so you'll need to do some detective work to figure out what the problem is.