Another advantage to using a 4 ohm woofer is significantly improved phase integration (was decent before, not sure about accuracy of this graph though)
The accuracy of that depends on a few things. First, that you are using the same type of phase data for both drivers (and that it's useful data), and second that you have an accurate setting for the offset (green circle) for both drivers.
For the first thing, most DIY people are using some type of minimum phase data, derived from the response either in their measurement program or later on in some other program. If you want Boxsim to use the phase data that was imported, you need to check the red-circled box. If you want Boxsim to derive it, uncheck the box. There are lots of workable combinations of ways to do it, and lots of ways for it to go wrong.
For the second thing, the most foolproof way a DIY person has to find the offset between drivers is to take three measurements (for a 2-way) from a single mic position: LF driver, HF driver, both drivers, or four where you add a second both-driver measurement with polarity swapped on HF. Then you simulate with single driver measurements, and adjust the offset (green circle) until it matches the both-driver measurements. For boxsim this needs to be measured on the axis midway between driver centers, which could be a problem for you because of the large size and off-axis ribbon rolloff.
In any case, the easiest way to check if the sim is at all accurate is to make a big null in the sim, such as by inverting one driver, and then try to measure it. If that isn't working you can be sure something is pretty wrong.
This is all normally totally critical stuff for a crossover design. I'm not sure how much difference getting it right will make here, though, because with such a high xover point and that spacing, getting it right might just be the difference between a vertical axis response at xover like shown below (except the off-axis lobes would be decreasing in magnitude quickly), and a more chaotic version of that.
You've probably got more of a challenge in finding a balance in sound power, since horizontally off-axis you're losing the middle of the spectrum but not much off the top, while vertically you lose the top and middle at least somewhat equally, or at least that's how I imagine this pans out, and Boxsim is not able to show you that at all (except when you have full off-axis information in the driver files like when you load the Visaton driver files).