"Pro" speakers can be quite nice, when they're oriented towards high fidelity.
I stuffed a pair of near-7 foot tall ElectroVoice VariplexB's in my bedroom for a while, and it sounded great, other than the drastic difference in height of where the frequencies were coming from:
(that's a 34" widescreen CRT for scale)
Driven by this rack:
My current living room system is a pair of EV Georgians as bass cabs with EAW CX-294 horn loaded 12" midranges:
(please ignore crossover HF setting, I had a really dirty switch)
These are my EV 30W's in utility cabs (I'm sure they were intended for professional use) with HPS SR-70's on top. The SR-70 is a Klipsch Heresy that's in a slightly bigger cabinet (I think) and is better built:
My friend's system that now occupies the same room is a bunch of VariplexB's and TL-770D's. I have the same exact speaker setup in storage for when I get space:
I also really like ElectroVoice Sentry 100A's, which I now have six of (seeing a trend here?

):
And, finally, in my bedroom system, I seem to have settled on ElectroVoice Sentry III's as my main speakers, and I really like them. Some might argue that they're more home oriented, but they were marketed to the professionals, and I believe found their first use in far more professional installations than home systems. (they now have the proper ST350A's):
There's a 50" plasma and Yamaha PC-5002M for scale.