I used a 250 for almost 30 years as my main amp but when I changed speakers after all that time they seemed to want just a hair more power and I started shopping around for a replacment. I finally ended up with a MC2105, the metered and glass faced version of the 2100. The sonic charactor of both of these amps is very close. The 3db more headroom helps a might in the bass power but I think the 250 had a might more detail as a tradeoff. Mids and highs when running the 2 amps at the same average power levels are all but the same. When I was shopping for my amp decades ago I compared the then in production units and from memory there was vitually no difference in sound on the speakers tested with that included KLH Nines, the speakers I used in my sytem, Bozaks 305s (today I use Symphonys that replaced the Nines), KLH 12 and 5s, McIntosh ML4 and 2, AR 3a and Wharfedale W70Ds. As the Nines had a maximum amp voltage that if exceeded could melt the wiring and the 2100/2105 exceeded the voltage, I stayed with the 250. In hindsight I'd like to have gotten the MC2505 back then and now would prefer the MC2100 over the MC2105. An issue of displaying those meters back then vs having space limitations requiring the 2105 to be hidden today.
The LaScalas I think are 104db for 1 watt. The question boils down to how much heardroom do you need and the dynamic range.
001 watts 104
002 107
004 110
008 113
016 116
032 119
064 121 (my MC250 puts out 75 watts rms per channel at well below the guarenteed specs)
128 123
I think audible pain sets in at about 120 db so the MC250 should be sufficient for the speakers. Must remember at average liseing levels we are talking about somewhere around 70 - 75db. Assuming Cds have a 40db dynamic range, the 250 should be pretty much in the slot for the LaScala with the 2100 more likely providing just a bit more headroom at the extreme dynamic range that possibly the 250 may clip at. This of course assumes no driver compression that should be less of a factor than with an acoustic suspension driver system.
As to what you woll hear will depend on the actual condition of each amp after all these years as they've aged and differences between your examples may be more than with mine.
In the FWIW deptartment, I have a set of Heresy IIs and at the same average amp power level (using a RS power meter) through my C28, I could perceive no difference in sound other than when I pushd them for dynamic range. I could clip the 250 first obviously but, at levels I could not stay in the same room as the speakers without starting to physically feel it.