For a typical road trip, I *try* to keep the driving time to about 8 hrs.
When we take the family to see my folks in Santa Fe, my 1st day stop over is Benson, AZ which is right about 460 miles or 8 hrs. That pretty much wipes me out for the day; just want a sit down dinner, a cold beer or two, then get some sleep for day 2.
My oldest son goes to college at Humboldt State/Arcata, CA.
We've made this round trip 6 times. My preferred route is 820 miles.
The routine usually goes two days to get up there, then coming back, I just want to get home so we power thru non-stop.
820 miles in one day with white knuckle driving the grapevine and then LA traffic takes a heavy toll.