The cheap ass material is superior to the expensive stuff.
If I was building speakers, I would go with some high quality plywood like birch or maple, preferably marine grade.
MDF is easy to work with and a good density for speakers, but it is poisonous. The dust is really bad for you, and you need to wear a mask when working with it. Also, it continues to gas out formaldehyde even after your speakers are built. I built some shelves out of MDF in my bedroom and had a sore throat for weeks. It's nasty stuff imo, and I'd rather not have it in my home. The smell makes me want to vomit.
MDF is for "While you were out" "carpenters". Real carpenters use real wood to build furniture. Speakers are furniture. Mine are cherry and sound quite nice. Line it with MDF? OK I guess. Why, I dunno.
Use common sence, this is not a space ship you build.
Use the best looking real wood (or veneer), don't listen to "scientists".
I like "appleply," a domestic variation of bb that comes in standard US sheet sizes up to 1.25" thick (bb maxes out at about .75" thick and only seems to come in 5'x5' sheets).Another product I've used in the past is baltic birch plywood. The baltic birch plys are are all the same thinkness whereas the plys in standard plywood vary in thickness and quite often contain voids (pockets of air) in the plys.
I like "appleply," a domestic variation of bb that comes in standard US sheet sizes up to 1.25" thick (bb maxes out at about .75" thick and only seems to come in 5'x5' sheets).